Here is a video from Matt Cutts explaining how to incorporate synonyms for important terms in your site. Matt says, if your site is targeting two keywords- EMR (Electronic Medical Records) and EHR (Electronic Health Records) , then its better to include both the keywords in the content of your webpage in a natural way in order to stop the search engines from guessing the relativity of both the keywords. This would give your site enough weight to rank for both of these keywords.
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